GEM 21S® Growth-Factor Enhanced Matrix
GEM 21S® is a regenerative material that may be used in select periodontal procedures to support healing around natural teeth when gum and bone defects are present.
A Scaffold Plus a Healing Signal
GEM 21S® combines two important parts: a synthetic bone-like scaffold called β-TCP and a purified growth factor called rhPDGF-BB.
In simple terms, the scaffold provides a framework, while the growth factor acts like a healing signal that helps attract and support the cells involved in periodontal regeneration.
GEM 21S® is being added to our periodontal treatment options for carefully selected cases. During your evaluation, Dr. Tutunaru will explain whether this material may be appropriate and what factors can affect healing, including the type of defect, oral hygiene, health history, smoking status, and follow-up care.
Note: PRF is different from GEM 21S®. PRF is made from the patient’s own blood. GEM 21S® is a separate regenerative material and does not require a blood draw.
Periodontal Defects GEM 21S® Is Designed For
GEM 21S® is indicated for certain periodontally related defects. A complete examination is needed to determine whether this treatment is appropriate for a specific patient.
Intrabony Periodontal Defects
Bone defects that form around a tooth as a result of periodontal disease.
Furcation Periodontal Defects
Defects that involve the area where the roots of a multi-rooted tooth divide.
Gingival Recession With Periodontal Defects
Gum recession cases where a periodontal defect is also present.
What Patients Can Expect
The exact procedure depends on the patient’s condition and the type of periodontal defect being treated. In general, treatment may include the following steps.
Careful Evaluation
Dr. Tutunaru evaluates the tooth, gums, bone support, x-rays, health history, and long-term prognosis.
Defect Preparation
The periodontal defect is carefully accessed and cleaned so the area can be prepared for regenerative treatment.
GEM 21S® Placement
When appropriate, GEM 21S® is placed into the periodontal defect as part of the regenerative procedure.
Healing & Follow-Up
Healing is monitored over time. Good home care, periodontal maintenance, and follow-up visits are important.
Not Every Case Is a Candidate
GEM 21S® may be a helpful option in select periodontal cases, but it is not appropriate for every patient or every type of bone defect.
A full exam is needed before recommending treatment. Factors such as active infection, medical conditions, medications, smoking, oral hygiene, tooth mobility, bone support, and the ability to maintain the area all matter.
Clear Expectations Matter
Regenerative procedures are designed to support healing, but no dental material can guarantee a specific result. Some cases may still require additional treatment, periodontal maintenance, or referral to a specialist.
Dr. Tutunaru will explain the findings, treatment options, expected benefits, limitations, risks, and alternatives before treatment.
Have You Been Told You Have Bone Loss or Gum Defects?
Call Country Club Dental to schedule an evaluation. We can review your x-rays, explain your options, and determine whether periodontal regenerative treatment may be appropriate.